DEFINITION AND PATHOGENESIS
- Benign neoplasm in which there are two or more types of cells of mesenchymal origin (not including fibrous tissue)
IMPORTANCE
- Recognition of the benign nature of the lesion to avoid overtreatment
- Mass ? pain
CLINICAL FEATURES
RADIOLOGIC FEATURES
- ? calcification if cartilage is present, suggesting a soft tissue chondrosarcoma
- ? fat demonstrated on CT or MRI (on T1 and STIR images)
GROSS PATHOLOGY
- Prominent pseudocapsule
- Hard mass
- Cut surface is glistening white when cartilage is present, ? interspersed fat
HISTOLOGIC FEATURES
- Chondrolipoangioma
- Hypercellular cartilage in focal areas
- Endochondral ossification in areas
- Areas of mature fat and blood vessels
DIFFERENTIAL CLINICOPATHOLOGIC DIAGNOSIS
- Soft tissue sarcoma
- Malignant mesenchymoma
DISEASE COURSE AND TREATMENT
- Excisional bx with minimal margins is adequate
SPECIAL CONSIDERATION
- CHONDROLIPOANGIOMA
- Contains cartilage, blood vessels, and fat
REFERENCES
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