DEFINITION AND PATHOGENESIS
- Formed of at least two unrelated types of tumor, not including fibrosarcoma and MFH
IMPORTANCE
- Rare, with only 8 reported cases in the literature as of 1983
CLINICAL FEATURES
- Most pts reported in the mid-teen years
- Fibular location accounting for a third of all cases
RADIOLOGIC FEATURES
- ? spiculated periosteal reaction, Codman triangle
- MRI may demonstrate an associated soft tissue mass
- Metaphyseal
GROSS PATHOLOGY
- Grayish yellow lobulated mass
HISTOLOGIC FEATURES
- Liposarcoma and osteosarcoma are the two most common malignant tissues of mesenchymal origin encoun-tered
- Sampling error may give initial dx of liposarcoma
DIFFERENTIAL CLINICOPATHOLOGIC DIAGNOSIS
- Osteosarcoma
- Liposarcoma
DISEASE COURSE AND TREATMENT
- High rate of LR
- Wide resection
REFERENCES
Bulychova IV, Unni KK, Bertoni F, Beabout JW: Fibrocartilagenous mesenchymoma of bone. Am J Surg Pathol 17:830-6,1993.
Reijnierse M, Kroon HM, Van Der Heul RO, Mulder JD: Mesenchymoma of bone. A case report. J Bone Joint Surg 75A:112-5,1993.
Scheele PM Jr, Von Kuster LC, Krivchenia G 2nd: Primary malignant nesenchymoma of bone. Arch Pathol Lab Med 14:614-7,1990.
Sumner TE, Ward WG, Kilpatrick SE, Opatowsky MJ: Fibrocartilaginous mesenchymoma of bone: case report and review of the literature. Pediatr Radiol 30:315-7,2000.
Last Updated on June 27, 2024
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