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Year |
2001 |
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Question Number |
158 |
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Category |
Select |
Question
In an animal model, the use of anabolic steroids on muscle injury has been shown to
1- be similar to placebo controls
2- be similar to corticosteroids with respect to muscle strength recovery in the long term
3- be more effective than corticosteroids with respect to muscle strength recovery in the long term
4- be less effective than corticosteroids with respect to muscle strength recovery in the long term
5- result in severely disorganized muscle fiber architecture.
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Answer (click for answer)
Answer 3
The referenced article is a study on rats and the effect of both anabolic and corticosteroids on muscle healing after contusion. With corticosteroids at day 2 the muscle showed improvement in twitch and strength relative to controls. At day 7 the effects were reversed and the muscles were significantly weaker than control. At day 14 the corticosteroid muscle was degenerated and showed disorganized muscle fibers. The anabolic steroid group showed greater force generating capacity at day 14 than controls.
The only acceptable answer is 3.
Reference: Beiner JM, Jokl P, Cholewicki J, Panjabi MM: The effect of anabolic steroids and corticosteroids on healing of muscle contusion injury. Am Sports Med 1999;27; 2-9
Tingus SJ, Carlsen RC: Effect of continuous infusion of an anabolic steroid on murine skeletal muscle. Med Sci Sports Exerc 1993; 25:485-494